An online game called Foldit was developed by folks at University of Washington response to scientists failed attempts to determine the structure for several years as reported in Nature Structural & Molecular Biology.
Which showed the power of a well crafted problem presented to a large mass of people.
The promise of this leads one to onder the application of a well crafted problem and the massess to all the problems in bioligy, physics, politics, finiance and any other field or problem of profound importance.